RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
mir-192
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
qRT-PCR; dual-luciferase reporter assay
Target
EGR1
Pathway
NA
PubMed ID
Title
MiR-192 prevents renal tubulointerstitial fibrosis in diabetic nephropathy by targeting Egr1
Year
2018
Function
miR-192 causes degradation of TGF-beta and fibronectin (FN) through targeting Egr2 and affects the progression of tubulointerstitial fibrosis (TIF) and even diabetic nephropathies.